What is one of the contraindications for obtaining ondansetron?

One of the contraindications for obtaining ondansetron is a known prolonged QT wave. Ondansetron is a medication used to prevent nausea and vomiting, particularly in patients undergoing chemotherapy or surgery. The concern regarding a prolonged QT interval is related to the risk of a potentially life-threatening arrhythmia known as Torsades de Pointes, which can occur when there is an abnormal heart rhythm caused by the lengthening of the QT interval. Patients with a known history of prolonged QT interval are at a heightened risk for these serious cardiac effects, making ondansetron use potentially dangerous for them.

Patients who have a history of migraines, are over the age of 70, or have an allergy to aspirin face different considerations but are not specifically contraindicated from using ondansetron in the same way that those with a prolonged QT interval are. For example, while age over 70 may require cautious use, it does not categorically prohibit the use of ondansetron like a known prolonged QT wave does.